Educational Articles
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Selegiline is typically given by mouth and is used off and on label to treat signs due to cognitive dysfunction syndrome, pituitary dependent Cushing’s disease, anxiety and certain phobias. Side effects may include vomiting, diarrhea, drooling, lack of appetite, and behavioral changes. Do not use in pets that are allergic to it, are aggressive, or in pets receiving other MAOIs, including certain tick collars. If a negative reaction occurs, please call your veterinary office.
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Sertraline is given by mouth and is used off label to treat behavior disorders in dogs and cats. Common side effects include tiredness, vomiting, diarrhea, lack of appetite, anxiety, irritability, sleeplessness, shaking, tremors, itchy skin, or panting. Do not use in pets that are allergic to it or other SSRIs, or pets that are using MAOIs, flea/tick collars, or cisapride. If a negative reaction occurs, please call your veterinary office.
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Ophthalmic autologous serum is a blood-derived product used to treat corneal ulcers in animals. Ophthalmic autologous serum is part of the blood and is collected directly from the patient. It is in liquid form.
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Sildenafil is given by mouth or injection and is used off label to treat high blood pressure in the lungs or to treat megaesophagus. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, or skin redness in the groin area. Do not use in pets that are allergic to it or pets that take nitrate medications. If a negative reaction occurs, please call your veterinarian.
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Slippery elm is given by mouth and is used over the counter to treat cough and stomach upset. Give as directed by your veterinarian. There are no known side effects. Do not use in pets that are allergic, pregnant, or nursing. If a negative reaction occurs, please call your veterinary office.
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Sodium chloride (hypertonic) ophthalmic is a topical medication used to reduce surface (corneal) swelling of the eye in cats and dogs. Sodium chloride is available without a prescription but should only be used under the direction of a veterinarian. It may be used “off label” or “extra label” to treat eye conditions in animals other than cats or dogs. Sodium chloride (hypertonic) ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulceration or dry eye.
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Sotalol is given by mouth or injection and is used off label in dogs and cats to treat abnormal heart rhythms. The most common side effect is tiredness. Do not use in pets that are allergic to it or that have asthma, heart block, slow heart rate, uncontrolled congestive heart failure, or shock. If a negative reaction occurs, please call your veterinary office.
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Soy protein is given by mouth and is used over the counter to treat many conditions such as urinary incontinence, certain cancers, inflammation, obesity, and diabetes. Side effects may include gastrointestinal signs, or allergic reactions. Do not use in pets that are allergic to it, or in pets that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.
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Spironolactone is given by mouth and is used off label to treat congestive heart failure, fluid accumulation, and other cardiovascular problems. Common side effects include increased drinking and urinating, mild decreases in energy, mild electrolyte imbalances, or vomiting/diarrhea. Do not use in pets that are allergic to it, have elevated potassium levels, Addison’s disease, acute kidney failure, significant kidney disease, that are not urinating or that may be used for breeding. If a negative reaction occurs, please call your veterinary office.
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Spironolactone/benazepril (brand name Cardalis®) is a combination aldosterone antagonist (spironolactone) and angiotensin-converting enzyme inhibitor or ACE inhibitor (benazepril) used to treat certain types of congestive heart failure in dogs. Use to treat other heart conditions or in other species is "off label" or "extra label". Spironolactone/benazepril comes in chewable meat-flavored tablet form.